Vasantha Padmanabhan Selected Research

Hyperandrogenism

1/2022	Androgen signaling in adipose tissue, but less likely skeletal muscle, mediates development of metabolic traits in a PCOS mouse model.
1/2021	Neurokinin 3 Receptor Antagonism Ameliorates Key Metabolic Features in a Hyperandrogenic PCOS Mouse Model.
1/2020	Developmental Programming: Sheep Granulosa and Theca Cell-Specific Transcriptional Regulation by Prenatal Testosterone.
1/2020	Mechanisms of intergenerational transmission of polycystic ovary syndrome.
11/2019	A Narrative Review of Placental Contribution to Adverse Pregnancy Outcomes in Women With Polycystic Ovary Syndrome.
10/2019	Developmental Programming: Contribution of Epigenetic Enzymes to Antral Follicular Defects in the Sheep Model of PCOS.
1/2017	Developmental Programming: Impact of Gestational Steroid and Metabolic Milieus on Mediators of Insulin Sensitivity in Prenatal Testosterone-Treated Female Sheep.
1/2017	Gestational Hyperandrogenism in Developmental Programming.
12/2016	Developmental Programming: Insulin Sensitizer Prevents the GnRH-Stimulated LH Hypersecretion in a Sheep Model of PCOS.
1/2015	Steroidogenic versus Metabolic Programming of Reproductive Neuroendocrine, Ovarian and Metabolic Dysfunctions.

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Vasantha Padmanabhan Research Topics

Disease

29	Insulin Resistance 01/2022 - 11/2005
28	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 01/2022 - 11/2005
17	Hyperandrogenism 01/2022 - 11/2005
9	Fetal Growth Retardation (Intrauterine Growth Retardation) 01/2022 - 02/2004
8	Body Weight (Weight, Body) 01/2022 - 04/2003
6	Inflammation (Inflammations) 01/2021 - 01/2017
5	Hypertension (High Blood Pressure) 01/2022 - 06/2007
5	Hyperinsulinism (Hyperinsulinemia) 11/2019 - 02/2006
4	Metabolic Diseases (Metabolic Disease) 06/2020 - 02/2016
4	Birth Weight (Birth Weights) 01/2020 - 10/2016
4	Anovulation 10/2019 - 10/2003
3	Obesity 01/2022 - 06/2007
3	Hypertrophy 01/2022 - 09/2015
3	Infertility (Sterility) 03/2009 - 02/2002
2	Cardiomegaly (Heart Hypertrophy) 01/2022 - 01/2016
2	Non-alcoholic Fatty Liver Disease 01/2022 - 10/2017
2	Overweight 12/2021 - 06/2020
2	Fibrosis (Cirrhosis) 01/2020 - 11/2019
1	Left Ventricular Dysfunction 01/2022
1	Hyperplasia 01/2022
1	Premature Birth (Birth, Premature) 01/2022
1	Type 2 Diabetes Mellitus (MODY) 12/2021
1	Weight Loss (Weight Reduction) 12/2021
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 09/2020
1	Fetal Weight 03/2020
1	Dosage-sensitive sex reversal 01/2020
1	Hypoxia (Hypoxemia) 11/2019
1	Pregnancy Complications 11/2019
1	Placental Insufficiency 11/2019

Drug/Important Bio-Agent (IBA)

38	Testosterone (Sustanon)FDA Link 01/2022 - 02/2004
17	Insulin (Novolin)FDA Link 01/2022 - 11/2005
13	AndrogensIBA 01/2022 - 04/2006
9	SteroidsIBA 01/2020 - 02/2004
8	bisphenol AIBA 01/2022 - 09/2013
6	LipidsIBA 01/2022 - 01/2018
6	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 11/2005
6	Estradiol (Delestrogen)FDA LinkGeneric 10/2017 - 10/2003
5	Hormones (Hormone)IBA 01/2022 - 02/2002
4	Triglycerides (Triacylglycerol)IBA 01/2022 - 03/2020
4	Gonadotropin-Releasing Hormone (GnRH)FDA Link 11/2019 - 01/2015
4	Luteinizing Hormone (Lutropin)FDA LinkGeneric 01/2015 - 11/2005
3	phthalic acid (phthalate)IBA 01/2022 - 10/2016
3	AntioxidantsIBA 03/2020 - 01/2017
3	Androgen Antagonists (Antiandrogens)IBA 01/2017 - 06/2012
2	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2022 - 01/2016
2	Androgen Receptors (Androgen Receptor)IBA 01/2022 - 01/2022
2	Estrogens (Estrogen)FDA Link 01/2022 - 04/2006
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2022
2	KisspeptinsIBA 01/2021 - 09/2015
2	Neurokinin BIBA 01/2021 - 09/2015
2	Dynorphins (Dynorphin)IBA 01/2021 - 09/2015
2	CollagenIBA 12/2020 - 01/2020
2	DNA (Deoxyribonucleic Acid)IBA 03/2020 - 01/2020
2	Interleukin-8 (Interleukin 8)IBA 03/2020 - 11/2019
2	PropionatesIBA 01/2020 - 03/2009
2	Endocrine DisruptorsIBA 01/2019 - 02/2016
2	AdiponectinIBA 01/2019 - 01/2017
2	Rosiglitazone (Avandia)FDA Link 01/2017 - 02/2016
2	Flutamide (Eulexin)FDA LinkGeneric 01/2017 - 02/2016
2	Insulin ReceptorIBA 10/2016 - 11/2010
2	Proteins (Proteins, Gene)FDA Link 01/2016 - 07/2004
2	Messenger RNA (mRNA)IBA 11/2010 - 04/2006
1	Atrial Natriuretic Factor (ANF)IBA 01/2022
1	monobutyl phthalateIBA 01/2022
1	mono-isobutyl phthalateIBA 01/2022
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 12/2021
1	CarbohydratesIBA 12/2021
1	Blood Glucose (Blood Sugar)IBA 01/2021
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2021
1	Nonesterified Fatty Acids (NEFA)IBA 01/2021
1	ChromatinIBA 09/2020
1	RNA (Ribonucleic Acid)IBA 09/2020
1	Polychlorinated Biphenyls (PCBs)IBA 06/2020
1	Estrogen Receptor betaIBA 03/2020
1	Insulin-Like Growth Factor Binding ProteinsIBA 03/2020
1	MethyltransferasesIBA 03/2020
1	Aromatase (CYP19)IBA 03/2020
1	IGF Type 2 Receptor (Insulin-Like-Growth-Factor II Receptor)IBA 03/2020
1	Hypoxia-Inducible Factor 1IBA 03/2020
1	Mixed Function Oxygenases (Monooxygenases)IBA 03/2020
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2020
1	Insulin-Like PeptidesIBA 03/2020
1	Histone Deacetylase 1IBA 03/2020
1	Steroid 17-alpha-Hydroxylase (17 alpha Hydroxylase)IBA 03/2020
1	Angiogenesis Inducing Agents (Angiogenesis Factor)IBA 03/2020
1	Histones (Histone)IBA 01/2020
1	EnzymesIBA 01/2020
1	Steroidogenic Factor 1IBA 01/2020
1	LigandsIBA 11/2019
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2019
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 11/2019
1	ChemokinesIBA 11/2019
1	C.I. direct red 80IBA 11/2019
1	Interleukin-6 (Interleukin 6)IBA 11/2019
1	Glutathione Reductase (Glutathione-Disulfide Reductase)IBA 11/2019
1	Superoxide Dismutase-1IBA 11/2019
1	Environmental Pollutants (Pollutants, Environmental)IBA 01/2019
1	PhenolsIBA 01/2019

Therapy/Procedure

1	Transplantation 01/2022
1	Glycemic Control 12/2021